Problems and countermeasures in the surveillance and research of wildlife epidemics based on mammals in China

doi:10.17520/biods.2020124

Abstract

Abstract:

Recent epidemics, such as the COVID-2019 pandemic, SARS, and rodent plague, pose a major threat to public health, food security, and ecosystem balance globally. These epidemics have all been caused, directly or indirectly, by pathogens found in mammals or other animal vectors. Based on the status of recent terrestrial wildlife epidemics in China, this study summarizes the regulatory and monitoring mechanisms for 24 important diseases occurring in wild mammals, captive breeding wild animals, and domesticated mammals in China, and then identifies gaps in regulation and knowledge for these zoonotic diseases in China. Due to the diversity of pathogens and their transmission routes, these zoonotic diseases have had frequent outbreaks in recent decades, and preventing and controlling them has become one major challenge. Currently, China’s important wildlife epidemics are monitored and controlled by different levels and directives of multiple governmental agencies. The increasing global trade, poaching, illegal wildlife trade, illegal wildlife captive breeding, consumption of wild animals, and lax quarantine processes have led to complex chains of transmission, increasing risk of contact, infection, and transmission of these diseases. Additionally, the frequent occurrence of extreme climate events or natural disasters further complicate the prevention and control of these wildlife epidemics at their sources. Based on these problems in managing and controlling new and recurrent epidemics in China, we propose some countermeasures and suggestions to strengthen basic research and whole-chain supervision in order to actively prevent terrestrial wildlife epidemics.

Key words: wildlife epidemics, mammals, prevention and control of epidemic focus and disease, gap analysis, basic research, whole-chain supervision

Zhishu Xiao, Libiao Zhang, Lei Xu, Qihai Zhou, Xiuxiang Meng, Chuan Yan, Gang Chang. Problems and countermeasures in the surveillance and research of wildlife epidemics based on mammals in China[J]. Biodiv Sci, 2020, 28(5): 566-578.

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URL: https://www.biodiversity-science.net/EN/10.17520/biods.2020124

https://www.biodiversity-science.net/EN/Y2020/V28/I5/566

References 61

[1]	Asokan GV, Asokan V, Fedorowicz Z, Tharyan P (2011) Use of a system approach and evidence-based One Health for zoonoses research. Chinese Journal of Evidence-based Medicine, 11, 845-848. (in Chinese)
	[ Asokan GV, Asokan V, Fedorowicz Z, Tharyan P (2011) 用系统方法和同一个健康理念研究种间传染病. 中国循证医学杂志, 11, 845-848.]
[2]	Auewarakul P, Hanchaoworakul W, Ungchusak K (2008) Institutional responses to avian influenza in Thailand: Control of outbreaks in poultry and preparedness in the case of human-to-human transmission. Anthropology & Medicine, 15, 61-67. DOI URL PMID
[3]	Chase J, Knight T (2003) Drought-induced mosquito outbreaks in wetlands. Ecology Letters, 6, 1017-1024.
[4]	Chen JC, Sun ZY, Ru YG, Liu SP (1998) Foot-and-mouth disease VIA antibody detected from imported wild animals. Chinese Journal of Veterinary Medicine, 24(11), 16. (in Chinese)
	[ 陈京彩, 孙振远, 茹亚光, 刘淑平 (1998) 进口野生动物检出口蹄疫VIA抗体. 中国兽医杂志, 24(11), 16.]
[5]	Cheng C, Wang WJ, Zhang K, Ma XJ, Li MY, Xu LH (2019) Serological investigation of paratraxis in dairy cows in Ningxia. Chinese Journal of Veterinary Medicine, 55, 62-64. (in Chinese)
	[ 程成, 王文佳, 张凯, 马小静, 李梦莹, 许立华 (2019) 宁夏地区奶牛副结核病血清学调查. 中国兽医杂志, 55, 62-64.]
[6]	Cheng YH, Wang M, Wang C, Ma LP, He TM, Wang PY (2018) The death investigation and protection strategies of gorals in subalpine areas of western Sichuan. Journal of Sichuan Forestry Science and Technology, 39(1), 54-58. (in Chinese with English abstract)
	[ 程跃红, 王敏, 王超, 马联平, 何廷美, 王鹏彦 (2018) 川西亚高山斑羚冬春季死亡调查及保护策略, 四川林业科技, 39(1), 54-58.]
[7]	Dirzo R, Young HS, Galetti M, Ceballos G, Isaac NJB, Collen B (2014) Defaunation in the Anthropocene. Science, 345, 401-406. URL PMID
[8]	Fang XY, Xu L, Liu QY, Zhang RZ (2011) Eco-geographic landscapes of natural plague foci in China: I. Eco-geographic landscapes of natural plague foci. Chinese Journal of Epidemiology, 32, 1232-1236. (in Chinese)
	[ 方喜业, 许磊, 刘起勇, 张荣祖 (2011) 中国鼠疫自然疫源地分型研究: I. 生态地理景观特征. 中华流行病学杂志, 32, 1232-1236.]
[9]	Feng N (2017) Epidemiological Investigation of Canine Distemper in Giant Pandas and Experimental Immunication Research. PhD dissertation, Jilin Agricultural University, Changchun. (in Chinese with English abstract)
	[ 冯娜 (2017) 大熊猫犬瘟热流行病学调查与实验免疫研究. 博士学位论文, 吉林农业大学, 长春.]
[10]	Gao GF (2018) From “A” IV to “Z” IKV: Attacks from emerging and re-emerging pathogens. Cell, 172, 1157-1159. URL PMID
[11]	Gao T, Su N (2013) Risk assessment and strategies after floods occurring in Beijing in 2012. Chinese Journal of Public Health Management, 29, 713-716. (in Chinese)
	[ 高婷, 苏宁 (2013) 2012年北京雨洪灾害后传染病疫情风险评估与应对策略. 中国公共卫生管理, 29, 713-716.]
[12]	Ge X, Li Y, Yang X, Zhang H, Zhou P, Zhang Y, Shi Z (2012) Metagenomic analysis of viruses from bat fecal samples reveals many novel viruses in insectivorous bats in China. Journal of Virology, 86, 4620-4630. DOI URL PMID
[13]	Gebreyes WA, Dupouy-Camet J, Newport MJ, Oliveira CJB, Schlesinger LS, Saif YM, Kariuki S, Saif LJ, Saville W, Wittum T, Hoet A, Quessy S, Kazwala R, Tekola B, Shryock T, Bisesi M, Patchanee P, Boonmar S, King LJ (2014) The global one health paradigm: Challenges and opportunities for tackling infectious diseases at the human, animal, and environment interface in low-resource settings. PLoS Neglected Tropical Diseases, 8, e3257. DOI URL PMID
[14]	Gubler D, Reiter P, Ebi K, Yap W, Nasci R, Patz J (2001) Climate variability and change in the United States: Potential impacts on vector- and rodent-borne diseases. Environmental Health Perspectives, 109(Suppl. 2), 223-233.
[15]	Jin YP, Liu QR, Sun M, Qiao YC, Qiao MM, Liu BH, Lin DG, Chen XZ (2015) Genomic characterization of the newly emerged canine distemper virus in giant panda. Scientia Agricultura Sinica, 48, 1445-1452. (in Chinese with English abstract) DOI URL
	[ 金艺鹏, 刘巧荣, 孙明, 乔雁超, 乔明明, 刘伯华, 林德贵, 陈西钊 (2015) 大熊猫源犬瘟热病毒基因组遗传特征分析. 中国农业科学, 48, 1445-1452.] DOI URL
[16]	Jin YP, Zhang XK, Ma YS, Qiao YC, Liu XB, Zhao KH, Zhang CL, Lin DG, Fu XL, Xu XR (2017) Canine distemper viral infection threatens the giant panda population in China. Oncotarget, 8, 113910-113919. DOI URL PMID
[17]	Jones KE, Patel NG, Levy MA, Storeygard A, Balk D, Gittleman JL, Daszak P (2008) Global trends in emerging infectious diseases. Nature, 451, 990-993. URL PMID
[18]	Lau SKP, Wong ACP, Zhang LB, Luk HKH, Kwok JSL, Ahmed SS, Cai JP, Zhao PSH, Teng JLL, Tsui SKW, Yuen KY, Woo PCY (2019) Novel bat alphacoronaviruses in southern China support Chinese horseshoe bats as an important reservoir for potential novel coronaviruses. Viruses, 11, 423. DOI URL
[19]	Li CW, Qu CM, Jin SY, He YG, Yang Q, Yang B, Wang CD, Liu SC, Li DS (2016) Analysis of serow mortality in Wolong Nature Reserve. Chinese Journal of Wildlife, 37(2), 147-150. (in Chinese with English abstract)
	[ 李才武, 瞿春茂, 金森燕, 何永果, 杨乾, 杨波, 王承东, 刘世才, 李德生 (2016) 卧龙自然保护区一鬣羚死亡原因剖析. 野生动物学报, 37(2), 147-150.]
[20]	Li FF, He XL, Cheng C, Wang WJ, Zhang K, Xu LH (2018) Advances in molecular detection of Mycobacterium bovis based on PCR. Chinese Journal of Veterinary Medicine, 54(5), 70-73. (in Chinese)
	[ 李凡飞, 何小丽, 程成, 王文佳, 张凯, 许立华 (2018) 基于PCR方法的牛分枝杆菌分子检测技术研究进展. 中国兽医杂志, 54(5), 70-73.]
[21]	Li HY, Zhu GJ, Zhang YZ, Zhang LB, Hagan EA, Martinez S, Chmura AA, Francisco L, Tai H, Miller M, Daszk P (2020) A qualitative study of zoonotic risk factors among rural communities in southern China. International Health, 12, 77-85. DOI URL PMID
[22]	Li JZ, Xia XZ, Hu GX, Fan ZQ, Zou XH, Wu YL, Huang G, Yuan SZ, Qiao GL (1999) Ecological investigation of canine distemper virus in China. Acta Veterinaria et Zootechnica Sinica, 34(4), 88-89,91-92. (in Chinese)
	[ 李金中, 夏咸柱, 胡桂学, 范志强, 邹啸环, 武银莲, 黄耕, 袁书智, 乔贵林 (1999) 我国犬瘟热病毒的生态学调查研究. 畜牧兽医学报, 34(4), 88-89,91-92.]
[23]	Li W, Shi Z, Ren M, Smith C, Epstein JH, Wang H, Crameri G, Hu Z, Zhang H, Zhang J, McEachern J, Field H, Daszak P, Eaton BT, Zhang S, Wang LF (2005) Bats are natural reservoirs of SARS-like coronaviruses. Science, 310, 676-679. URL PMID
[24]	Li WD, Liang GD, Liang B, Hu ZH, Shi ZL, Zhang SY (2004) Progress of research on the viruses in bats. Virologica Sinica, 19, 418-425.(in Chinese with English abstract).
	[ 李文东, 梁国栋, 梁冰, 胡志红, 石正丽, 张树义 (2004) 蝙蝠携带病毒的研究进展. 中国病毒学, 19, 418-425.]
[25]	Li XY, Ma RL, Wang YP, Zhang LC, Fu YJ, Wang XZ, Zhang MH, You XQ (2016) Monitoring and prevention strategy of peste des petits Ruminants in Qinghai Province. Chinese Journal of Veterinary Medicine, 52(11), 126-127. (in Chinese)
	[ 李秀英, 马睿麟, 王云平, 张立成, 傅义娟, 王谢忠, 张茂华, 游潇倩 (2016) 青海省小反刍兽疫的监测与防范策略. 中国兽医杂志, 52(11), 126-127.]
[26]	Liu YY (2009) Fast evaluation and disease surveillance. South China Journal of Preventive Medicine, 35(1), 65-68. (in Chinese)
	[ 刘勇鹰 (2009) 地震灾害现场快速评估与疾病监测. 华南预防医学, 35(1), 65-68.]
[27]	Liu YY, Zhang YR, Liu XL, Lin LF, Liu YF, Peng ZQ (2008) Disease surveillance and risk evaluation on the transmission of infectious disease in emergent status after earthquake. South China Journal of Preventive Medicine, 34(4), 9-12. (in Chinese with English abstract)
	[ 刘勇鹰, 张玉润, 刘小立, 林立丰, 刘于飞, 彭志强 (2008) 地震灾区紧急状态下的疾病监测与传染病流行风险评估. 华南预防医学, 34(4), 9-12.]
[28]	Loots AK, Mitchell E, Dalton DL, Kotzé A, Venter EH (2016) Advances in canine distemper virus (CDV) pathogenesis research: A wildlife perspective. Journal of General Virology, 98, 311-321. URL PMID
[29]	Nie YB, Qiao J (2019) Impact of African swine fever on the development of pig industry in China. Journal of Agricultural Science and Technology, 21(1), 11-17. (in Chinese)
	[ 聂赟彬, 乔娟 (2019) 非洲猪瘟发生对我国生猪产业发展的影响. 中国农业科技导报, 21(1), 11-17.]
[30]	Nunn CL, Altizer S (2006) Infectious Diseases in Primates: Behavior, Ecology and Evolution. Oxford University Press, Oxford & New York.
[31]	Old JM, Sengupta C, Narayan E, Wolfenden J (2017) Sarcoptic mange in wombats—A review and future research directions. Transboundary & Emerging Diseases, 65(8), 1-9.
[32]	Olival KJ, Epstein JH, Wang LF, Field HE, Daszak P (2012) Are bats unique virus reservoirs?In: New Directions in Conservation Medicine: Applied Cases of Ecological Health (eds Aquirre AA, Ostfeld RS, Daszak P), pp. 195-212. Oxford University Press, New York.
[33]	Patrono LV, Samuni L, Corman VM, Nourifa L, Röthemeier C, Wittig RM, Drosten C, Calvignac-Spencer S, Leendertz FH (2018) Human coronavirus OC43 outbreak in wild chimpanzees, Côte d’Ivoire, 2016. Emerging Microbes & Infections, 7, 118-121. DOI URL PMID
[34]	Peeters M (2004) Cross-species transmissions of simian retroviruses in Africa and risk for human health. Lancet, 363, 911-912. DOI URL PMID
[35]	Perovic VR, Muller CP, Niman HL, Veljkovic N, Dietrich U, Tosic DD, Glisic S, Veljkovic V (2013) Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1- HPAIV reveals evolution toward efficient human-to-human transmission. PLoS ONE, 8, e61572. DOI URL PMID
[36]	Riou J, Althaus CL (2020) Pattern of early human-to-human transmission of Wuhan 2019 Novel Coronavirus (2019-nCoV), December 2019 to January 2020. Eurosurveillance, 25, 2000058.
[37]	Rouguet P, Froment JM, Bermejo M, Kilbourn A, Waresh W, Reed P, Kumulungui B, Yaba P, Délicat A, Rollin PE, Leroy EM (2005) Wild animal mortality monitoring and human Ebola outbreaks, Gabon and Republic of Congo, 2001-2003. Emerging Infectious Diseases, 11, 283-290. DOI URL PMID
[38]	Shan C, Yao YF, Yang XL, Zhou YW, Wu J, Gao G, Peng Y, Yang L, Hu X, Xiong J, Jiang RD, Zhang HJ, Gao XX, Peng C, Min J, Chen Y, Si HR, Zhou P, Wang YY, Wei HP, Pang W, Hu ZF, Lv LB, Zheng YT, Shi ZL, Yuan ZM (2020) Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in the Rhesus macaques. Infectious Diseases. Doi: 10. 21203/rs. 2. 25200/v1. URL PMID
[39]	Song G (2000) The main achievements in the prevention and treatment of epidemic hemorrhagic fever in New China. Chinese Journal of Epidemiology, 21(5), 58-62. (in Chinese)
	[ 宋干 (2000) 新中国流行性出血热防治研究的主要成就. 中华流行病学杂志, 21(5), 58-62.]
[40]	Sun Z, Xu L, Schmid BV, Dean KR, Zhang Z, Xie Y, Fang X, Wang S, Liu Q, Lyu B, Wan X, Xu J, Stenseth NC, Xu B (2019) Human plague system associated with rodent diversity and other environmental factors. Royal Society Open Science, 6, 190216. DOI URL PMID
[41]	Taylor LH, Latham SM, Woolhouse MEJ (2001) Risk factors for human disease emergence. Philosophical Transactions of the Royal Society B, 356, 983-989. DOI URL
[42]	Wan KL (1998) Research status and prospect of Lyme disease in China. Chinese Journal of Vector Biology and Control, 9(6), 5-9. (in Chinese)
	[ 万康林 (1998) 中国莱姆病的研究现状与展望. 中国媒介生物学及控制杂志, 9(6), 5-9.]
[43]	Wang GM (2019) The implementation of prevention of peste des petits ruminants and the problems faced in Tianjun Town. Chinese Qinghai Journal of Animal and Veterinary Sciences, 49(4), 69-70. (in Chinese)
	[ 王光明 (2019) 天峻县小反刍兽疫防控工作开展情况及面临的问题. 青海畜牧兽医杂志, 49(4), 69-70.]
[44]	Wang MB, Zhang JJ, Liu H, Jie LJ, Jiang SX, Wang HZ (2009) Public health condition and epidemics risk after earthquake in Beichuan. Chinese Journal of Public Health, 25, 1271. (in Chinese)
	[ 王茂波, 张建军, 刘洪, 接令均, 蒋善祥, 王合章 (2009) 北川县震后公共卫生状况及传染病流行风险. 中国公共卫生, 25, 1271.]
[45]	Wang YY, Li N, Chen GL, Wang KC, Yuan JG, Zhang MJ (2018) An emergency epidemiological investigation on deer Clostridiosis welchii in Chengde City of Hebei Province. China Animal Health Inspection, 35(3), 14-16. (in Chinese)
	[ 王圆圆, 李宁, 陈国亮, 王楷宬, 袁建国, 张淼洁 (2018) 河北省承德市一起鹿魏氏梭菌病的紧急流行病学调查. 中国动物检疫, 35(3), 14-16.]
[46]	Wang ZM, Jia GL, Wang JB, Lin XM, Han XQ, Zhang Y (2010) Progress in studies on pathogen of Bovine tuberculosis. China Animal Husbandry & Veterinary Medicine, 37, 207-210. (in Chinese)
	[ 王志梅, 贾广乐, 王建波, 林祥梅, 韩雪清, 张映 (2010) 牛结核病病原体研究进展. 中国畜牧兽医, 37, 207-210.]
[47]	Wu QX, Pei JF, Jin XL, Xian YH, Chang LL, Che LF, Li FF, Zhao ZM, Shen J, Liu YQ (2019) Investigation of death causes of wild gorals in Qinling Mountains. Progress in Veterinary Medicine, 40(12), 136-139. (in Chinese with English abstract)
	[ 吴桥兴, 裴俊峰, 金学林, 县怡涵, 常玲玲, 车利锋, 李芳芳, 赵泽明, 沈洁, 刘育强 (2019) 秦岭野生斑羚死亡原因调查. 动物医学进展, 40(12), 136-139.]
[48]	Xiao ZS, Li XH, Wang XZ, Zhou QH, Quan RC, Shen XL, Li S (2014) Developing camera-trapping protocols for wildlife monitoring in Chinese forests. Biodiversity Science, 22, 704-711. (in Chinese with English abstract)
	[ 肖治术, 李欣海, 王学志, 周岐海, 权锐昌, 申小莉, 李晟 (2014) 探讨我国森林野生动物红外相机监测规范. 生物多样性, 22, 704-711.]
[49]	Xu L, Schmid B, Liu J, Si X, Stenseth N, Zhang Z (2015) The trophic responses of two different rodent-vector-plague systems to climate change. Proceedings of the Royal Society B: Biological Sciences, 282, 20141846.
[50]	Xu L, Stige LC, Leirs H, Neerinckx S, Gage KL, Yang R, Liu Q, Bramanti B, Dean KR, Tang H, Sun Z, Stenseth NC, Zhang Z (2019) Historical and genomic data reveal the influencing factors on global transmission velocity of plague during the Third Pandemic. Proceedings of the National Academy of Sciences, USA, 116, 201901366.
[51]	Yang GY, Yang XC (1997) The investigation of sarcoptic mange outbreak in sumen in Jiuzhaigou Nature Reserve. Sichuan Journal of Zoology, 16(2), 86. (in Chinese with English abstract)
	[ 杨光友, 杨学成 (1997) 九寨沟自然保护区苏门羚群发性疥螨病的调查. 四川动物, 16(2), 86.]
[52]	Ying L, Yang YQ, Li L, Zhao QB, Wang XZ, La H, Liu FX, Tan SK, Song LZ, Wu XD, Cai JS (2019) Diagnosis and control of the first peste des petits ruminants infecting wild Pseudois nayaur in the Qinghai Plateau area. Animal Husbandry & Veterinary Medicine, 51(12), 112-117. (in Chinese)
	[ 应兰, 杨毅青, 李林, 赵全邦, 王谢忠, 拉华, 刘拂晓, 谭生魁, 宋龙智, 吴晓东, 蔡金山 (2019) 青海高原首例岩羊小反刍兽疫诊断与控制. 畜牧与兽医, 51(12), 112-117.]
[53]	Zeng Y, Ping XG, Wei FW (2020) A conceptual framework and definitions for the term “wild animal”. Biodiversity Science, 28, 541-549.(in Chinese with English abstract).
	[ 曾岩, 平晓鸽, 魏辅文 (2020) “野生动物”的概念框架和术语定义. 生物多样性, 28, 541‒549.]
[54]	Zhang CL, Liu Y, Zhao J, Jia T, Yang MH, Pu TC, Ding N, Zheng CM, Yuan L, Zhang JG (2011) Clostridial gastroenteritis and its prevention in herbivorous artiodactyls. Chinese Journal of Wildlife, 32(6), 336-342. (in Chinese)
	[ 张成林, 刘燕, 赵京, 贾婷, 杨明海, 普天春, 丁楠, 郑常明, 原蕾, 张金国 (2011) 草食偶蹄动物魏氏梭菌病及预防. 野生动物, 32(6), 336-342.]
[55]	Zhang HL, Shi HF, Liu LH, Yu RX, Zi DY, Li ZX, Zhang TS, Cui WQ, Wang ZW, Guo ZM, Li XN, Jia L (1989) Isolation of Chikungunya virus from bat in Yunnan Province and serological investigations. Chinese Journal of Virology, 5, 31-36. (in Chinese)
	[ 张海林, 施华芳, 刘丽华, 俞永新, 自登云, 李兆祥, 张天寿, 崔五全, 王志伟, 国正鸣, 李新年, 甲利 (1989) 从云南省蝙蝠中分离基孔肯雅病毒及血清抗体调查. 病毒学报, 5, 31-36.]
[56]	Zhang HL, Tao SJ, Zhang YZ (2006) Research of arboviruses in the lower reaches areas of Lancang River, Yunnan Province. Chinese Journal of Experimental and Clinical Virology, 20(1), 95-98. (in Chinese)
	[ 张海林, 陶三菊, 张云智 (2006) 云南省澜沧江下游地区虫媒病毒研究状况. 中华实验和临床病毒学杂志, 20(1), 95-98.]
[57]	Zhang HL, Zhang YZ, Huang WL, Mi ZQ, Gong HQ, Wang JL (2001) Isolation of Japanese encephalitis virus from brain tissues of bat in Yunnan Province. Chinese Journal of Virology, 16(1), 74-77. (in Chinese)
	[ 张海林, 张云智, 黄文丽, 米竹青, 龚鹤琴, 王静林 (2001) 从云南省蝙蝠脑组织中分离出乙型脑炎病毒. 中国病毒学, 16(1), 74-77.]
[58]	Zhang HY, Lu ZH, Yang X, Wang YB, Jin Y (2004) The epidemic characteristics of Clostridiosis wijeldiem in China. China Animal Husbandry & Veterinary Medicine, (1), 39-41. (in Chinese)
	[ 张红英, 卢中华, 杨霞, 王亚宾, 金钺 (2004) 我国魏氏梭菌病的流行特点. 中国畜牧兽医, (1), 39-41.]
[59]	Zhang XY, Liu CJ, Wang ZL, He ZY (2007) Risk analysis of the introduction of peste des petits ruminants (PPR) into China. China Animal Health Inspection, 24(10), 40-42. (in Chinese)
	[ 张喜悦, 刘春菊, 王志亮, 何昭阳 (2007) 小反刍兽疫(PPR)传入我国的风险分析. 中国动物检疫, 24(10), 40-42.]
[60]	Zhao PP, Zhang GS, Han XL, Shen JN, Zhang DH, Pan GL, Zhang Q, Hou J, Ma QY, Gao GG (2017) Diagnosis, treatment and prevention of canine distemper in giant pandas. Progress in Veterinary Medicine, 38(9), 115-118. (in Chinese with English abstract)
	[ 赵鹏鹏, 张国士, 韩学利, 沈洁娜, 张丹辉, 潘广林, 张强, 侯佳, 马清义, 高更更 (2017) 熊猫犬瘟热的诊治及预防对策. 动物医学进展, 38(9), 115-118.]
[61]	Zhou P, Fan H, Lan T, Yang XL, Shi WF, Zhang W, Zhu Y, Zhang YW, Xie QM, Mani S, Zheng XS, Li B, Li JM, Guo H, Pei GQ, An XP, Chen JW, Zhou L, Mai KJ, Wu ZX, Li D, Anderson DE, Zhang LB, Li SY, Mi ZQ, He TT, Cong F, Guo PJ, Huang R, Luo Y, Liu XL, Chen J, Huang Y, Sun Q, Zhang XLL, Wang YY, Xing SZ, Chen YS, Sun Y, Li J, Daszak P, Wang LF, Shi ZL, Tong YG, Ma JY (2018) Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin. Nature, 556, 255-258. DOI URL PMID