Abstract: Biodiversity is , in nature , a kind of highly comprehensive and multi-valued resource on which human society depends for survival and development . The conservation and utilization of biodiversity resources often conflict against each other during the development of human society , but can be harmonized. The management of biodiversity resources is the fundamental approach to keep the two issues of realizing sustainable utilization of biodiversity resources and the sustainable development of regional social economy in harmony. Management , composed of subject layer , object layer and target layer , is a complex , hierarchical and dynamic feedback process with six basic steps , which should have features in the diversity of subject components , universality of participation , dynamic and persistence of the process , differentiation according to scale and region , and equity. The subject layer , made of various groups of people , is a functional layer derives from socio-economic system. The object layer ,the focus of management , is the coupling of biodiversity resources system and socio-economic system. The target layer comprises the sustainable utilization of iodiversity resources , the establishment and development of eco-civilization and the sustainable development of regional socio-economy. Eco-civiliza- tion is the very guarantee of the other two. The subject layer and object layer are entitative components of the management , and the target layer is the frame of reference. The six basic steps are area define ,problem recognition , object establishment , policy making and planning , implementation , monitoring and evaluation , and adaptation. Scientific researches play important roles in the management process.Therefore , it is urgent to fill the gaps between science and management to transform scientific fruits into effective management activities during the intensification of biodiversity research.